WHAT IS GUIDED TISSUE
REGENERATION
AND WHERE CAN IT BE USED?
TEETH AND IMPLANTS
Your teeth are at risk because of periodontal disease. It
began with the buildup of plaque and tartar on your teeth, which may have
resulted from insufficient brushing and flossing. Over time, the plaque and
tartar have caused loss of the supporting tissue around some of your teeth.
When plaque builds up on a tooth, bacteria in the plaque
attack the bone around the tooth as well as the fibers which connect the tooth
to the bone. As the fibers and bone are destroyed, a pocket or space forms
between the gum and the tooth- an ideal site for more plaque to build up. Without
proper hygiene the process may continue, sometimes without symptoms, until the tooth is
endangered.
WHAT CAN BE DONE TO PREVENT TOOTH LOSS OR
INCREASE BONE FORMATION FOR IMPLANT PLACEMENT.

Guided Tissue Regeneration (GTR) is a procedure that
enables bone and tissue to regrow around an endangered tooth OR IF THE TOOTH IS
LOST, to increase bone for implant placement either pior to or at time of
placement. This is different
from other periodontal therapies where regrowth of the bone and the tissue is
often limited or highly unpredictable. Conventional therapies for periodontal
treatment have often involve
removal of soft (gum) tissue to reduce pocket depths. This would leave a greater portion
of the tooth exposed, resulting in a less pleasing appearance.
In GTR therapy for teeth, the soft (gum) tissue is surgically separated from the
endangered tooth and the tooth surface is thoroughly cleaned. Infected tissues
are removed from the area. Next a small piece of material called a GTR membrane
is placed against the tooth. If the tooth
is to be removed and an implant placed, the soft tissue is then sutured back into place, covering
the implant if placed and the membrane. Platelet Rich Plasma, PRP can also
be used and within a few days, the healing process is proceeding.
EXTRACTION, PRP, AND GTR WITH
IMMEDIATE IMPLANT PLACEMENT
Photographs
of CLINICAL CASE

1) Unhealthy supporting
bone structure for tooth.
2) Placement of PRP and a barrier over dental implants with sutures to promote
regeneration.
3) Barrier about to be removed with formation of new bone and supporting
tissue.
4) Healthy, regenerated bone and soft tissue with implants in place.
RADIOGRAPHS OF CLINICAL CASE

Healthy, regeneration of
new bone and supporting tissue with implants in place.
This type of treatment is appropriate for many types of
problems. The type and severity of bone and soft tissue loss, your willingness to
maintain appropriate oral hygiene, and whether or not you smoke, are factors
considered by your dental professional when choosing an appropriate therapy. GTR
can improve the condition caused by periodontal disease within six to eight
weeks, although complete healing may not be achieved for six months. During this
time, the healing wound must be protected from trauma for several weeks.
Photographs
of CLINICAL COMPLETED CASE

RADIOGRAPHS OF
COMPLETED CLINICAL CASE

Healthy, regeneration of
new bone and supporting tissue with implants,custom abutments
& crowns in place.
WHAT CAN I EXPECT FROM GTR?
This is how GTR works: the GTR membrane
serves as a barrier that separates fast-growing soft (gum) tissue from the newly
cleaned surface of the tooth root. This enables slower-growing fibers and bone
cells to migrate into the protected area.
Absorbable collagen membrane can be used
and removal of the membrane is
unnecessary. It will be completely and naturally dissolved in approximately
eight weeks following surgery. Incases of bone regeneration with an
extraction site, a nonresorbable membrane will be needed during the time of
regeneration
Collagen is a natural material that has
been used for many years in medical products. Collagen is the most abundant
protein in the animal kingdom and is made of
bovine Achilles tendon, one of the purest sources of Type I collagen available.

1) Unhealthy supporting structure for a tooth.
2) Placement of the barrier to promote the regeneration process.
3) New formation of bone and healing tissue.
4) Healthy, regenerated gums.
WHAT CAN MY DOCTOR DO TO HELP?
Prior to GTR therapy, your dental professional will recommend
an appropriate oral hygiene program. It is essential that you follow this
program, otherwise, GTR therapy has less chance of success and may be ruled out
as a treatment option.
THE USE OF PRP WITH GTR
The surgeon draws approximately 50cc of your blood at the time of surgery.
The blood is placed in a specialized centrifuge that spins and automatically
separates the red blood cells from the plasma. The plasma is then further
centrifuged to concentrate the autologous platelets and hence your natural
growth factors. The Platelet Rich Plasma (PRP) is then available for your surgeon to use as needed. The
entire process takes less than 5 minutes and adds no extra time to the surgical
procedure.
WHAT IS PLATELET RICH PLASMA (PRP)?
Platelet Rich Plasma (PRP) is composed of platelets and plasma. Platelets are
tiny cells that are partially responsible for causing blood to clot. Platelets
also contain large reservoirs of natural growth factors. While a normal
concentration of platelet circulating in your blood is 200,000 per micro liter,
the platelet count in PRP can exceed 2 million platelets per micro liter.
WHAT ARE GROWTH FACTORS?
Platelets contain potent growth factors necessary to begin tissue repair and
regeneration at the wound site. Growth factors derived from platelets initiate
connective tissue healing, bone regeneration and repair, promote
development of new blood vessels, and stimulate the wound healing process.
IS PRP FOR YOU?
The use of PRP enriched with growth factors is considered by many to be a
"new frontier" of clinical therapy. Since PRP can he used in so many
types of procedures and for so many
types of patients, you should
discuss your specific surgery with your doctor.
Following GTR
therapy
Following GTR therapy, your doctor will provide specific
instructions for proper oral hygiene and care of the area under treatment. These
may include the following:
• It is important not to disturb the GTR membrane or the
tissue that covers it. Your doctor may ask you to refrain from brushing or
flossing the treated area for some time following the procedure to avoid damage
to healing tissues.
• Specific mouthwashes may be recommended to reduce plaque
buildup.
• Your doctor may prescribe an antibiotic to reduce the
possibility of a bacterial infection in the surgical area.
• You will be scheduled for postoperative visits.
These appointments are important as they allow your doctor to
evaluate wound healing and professionally clean the treated area, if necessary.
• If the GTR membrane becomes exposed, or if other problems
occur, consult your doctor for additional instructions.
• Some discomfort should be expected following surgery.
This is normal for any form of periodontal surgery. When PRP is used, there is no second surgery or additional
discomfort.
When your doctor determines that treatment and healing are
complete, you may return to a normal hygiene regimen.
It is important to keep in mind that proper hygiene is
essential to prevent a serious recurrence of periodontal disease. For many
patients, this means adhering more stringently to hygiene practices than in the
past since inadequate hygiene was probably a primary factor in the onset of the
disease.
For these reasons, you should review your brushing and
flossing practices with your doctor and make a long-term commitment to following
your doctor’s prescribed regimen.
If you have any questions regarding the GTR procedure, do not
hesitate to discuss it with your doctor.
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